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February ECD Citation list is now available

HELP’s February 2015 ECD citation list is now available. The citation list includes Early Child Development academic research publications for February 2015 and pre-prints for March and beyond. This month's list includes new research publications by HELP's affiliated scholars, Michael Kobor and Joanne Weinberg. As well, there is an Australian EDI publication and a new publication from Lucy Le Mare.

Our monthly citation list is also posted to the HELP Publications page of our website. This page offers direct links to key HELP researcher publications as well as links to monthly ECD citation lists (from as far back as June 2011).  The February PDF is located on the right hand side menu under the heading “ECD References”.


Michael Kobor receives award of excellence

HELP congratulates Dr. Michael Kobor as one of the recipients of the inaugural Child and Family Research Institute (CFRI) Member & Staff Recognition Awards.

On March 12, 2013, it was announced that Dr. Kobor will be recognized with the Award of Excellence, Biomedical Research. Dr. Kobor is a scientist at the Centre for Molecular Medicine and Therapeutics.  He is an Associate Professor at UBC's Department of Medical Genetics and the Human Early Learning Parthership (HELP).

The award recipients have long-standing and distinguished research careers that are recognized locally, nationally and internationally. Their work serves as outstanding examples of excellence and innovation that has significantly contributed to the health and well-being of children and families. A formal awards ceremony will take place in Fall 2013.

For more information: www.cfri.ca


Kobor, CMMT study shows genes and immune system shaped by childhood poverty, stress

A University of British Columbia and Centre for Molecular Medicine and Therapeutics (CMMT) study has revealed that childhood poverty, stress as an adult, and demographics such as age, sex and ethnicity, all leave an imprint on a person’s genes. And, that this imprint could play a role in our immune response.

The study was published last week in a special volume of the Proceedings of the National Academy of Sciences that looks at how experiences beginning before birth and in the years after can affect the course of a person’s life.

Known as epigenetics, or the study of changes in gene expression, this research examined a process called DNA methylation where a chemical molecule is added to DNA and acts like a dimmer on a light bulb switch, turning genes on or off or setting them somewhere in between. Research has shown that a person’s life experiences play a role in shaping DNA methylation patterns.

The research team discovered that childhood poverty, but not socioeconomic status as an adult, was correlated with the marks or methylation patterns left on genes.

“We found biological residue of early life poverty,” said Michael Kobor, an associate professor of medical genetics ...

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CIHR CAFÉ SCIENTIFIQUE - Epigenetics, and how early experiences may affect your health later in life

What causes the complex illnesses associated with aging, like cancer and heart disease? Each day we discover new genes associated with these diseases. But as we learn more about the genetic code, it becomes clearer that what’s written in our DNA is only part of the story. There are other factors, such as socioeconomic status, that seem to play an important role in health.

Now a new area of research, known as epigenetics, is building upon our knowledge of the human genome. Epigeneticists study the ways that our environment can have a long-term impact on the activity of our genes. And recent advances in technology are giving researchers remarkable new tools to study how nature interacts with nurture.

Date: March 27, 2012
Time: 7:00pm
Where: Granville Island Hotel, 1253 Johnston St., Vancouver
Cost: Free
Hosted by: CIHR and its Institute of Neurosciences, Mental Health and Addiction in collaboration with the Canadian Epigenetics, Environment and Health Research Consortium.

Experts:
Dr. W. Thomas Boyce, PhD
Professor, Sunny Hill Health Centre/BC Leadership Chair in Child Development
School of Population and Public Health and Faculty of Medicine, UBC

Dr. Martin Hirst, PhD
Scientist, Canada’s Michael Smith Genome Sciences Centre, BC ...

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Now online: Presentations from the December 2011 Arthur M. Sackler Colloquia of the National Academy of Sciences

Entitled Biological Embedding of Early Social Adversity: From Fruit Flies to Kindergarters, the Sackler Colloquia focused on socioeconomic position as the single most powerful determinant of health and development within every human society on earth. Rapidly accumulating evidence suggests that differential exposure to early childhood adversities contributes strongly to the observed social disparities in mental and physical health, cognitive and socioemotional development, and lifetime educational and economic attainment. Studies in a broad array of species, ranging from invertebrates to human and nonhuman primates, are elucidating fundamental mechanisms by which social stratification is induced and maintained and by which socially partitioned adversities are transduced into neurobiological and genomic processes. Using new developmental neurogenomic approaches, science is poised to finally understand why disease, disorder and developmental misfortune are so unevenly distributed within human populations. This colloquium convened a world class, cross disciplinary assembly of basic, biomedical, and social scientists to explore the biological embedding of early social adversity across multiple species, from fruit flies to human kindergartners.

Speakers included Clyde Hertzman, Tom Boyce, Janet Werker, Michael Kobor and many others. See HELP researcher presentation below and visit the Sackler Colloquia's YouTube Channel to view the other presentations.

The Arthur M. Sackler ...

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